Development of a Predictive Enrichment Marker for the Oral GH Secretagogue LUM-201 in Pediatric Growth Hormone Deficiency.

George M Bright Minh-Ha T Do John C McKew Werner F Blum Michael O Thorner

Published in: Journal of the Endocrine Society (2021)

Combined, the peak GH response to single-dose LUM-201 and the baseline IGF-I concentration are effective PEMs for 6-month growth responses to LUM-201 and rhGH in prepubertal children with GHD.

Keyphrases

growth hormone
young adults
recombinant human
replacement therapy
cell proliferation
binding protein