Reflex Xpert MTB/XDR Testing of Residual Rifampicin-Resistant Specimens: A Clinical Laboratory-Based Diagnostic Accuracy and Feasibility Study in South Africa.

C M CentnerR MunirE TaglianiF RießP BrownC HayesT DolbyW ZemanayD M CirilloA DavidS G SchumacherClaudia M DenkingerM RuhwaldV N LeukesM P NicolI Van der WaltG KistenM GumedeA MaceA BrinkW StevensL ScottAdam Penn-Nicholson Helen Coxnull null

Published in: Open forum infectious diseases (2024)

Xpert MTB/XDR performed favorably compared with the reference, and the reflex testing approach increased results availability over routine testing, while dramatically decreasing turnaround time from weeks to hours. Laboratory workflow precluded testing within the manufacturer-recommended 4-hour storage time, but longer storage did not appear detrimental.

Keyphrases

mycobacterium tuberculosis
south africa
pulmonary tuberculosis
drug resistant
blood pressure
gestational age