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Inflammatory activity affects the accuracy of liver stiffness measurement by transient elastography but not by two-dimensional shear wave elastography in non-alcoholic fatty liver disease.

Yuly P MendozaSusana G RodriguesMaria G DelgadoGiuseppe MurgiaNaomi F LangeJonas SchroppMatteo MontaniJean-François DufourAnnalisa Berzigotti
Published in: Liver international : official journal of the International Association for the Study of the Liver (2021)
Inflammatory activity on histology significantly affects LSM by TE, but not LSM by 2D-SWE in NAFLD. LSM by 2D-SWE reflects liver fibrosis more accurately than LSM by TE. Furthermore, the severity of steatosis on histology did not influence the association of LSM and fibrosis by either elastography method.
Keyphrases
  • liver fibrosis
  • oxidative stress
  • adipose tissue
  • skeletal muscle