Advanced high-grade serous ovarian cancer: inverse association of KLK13 and KLK14 mRNA levels in tumor tissue and patients' prognosis.

Larissa DettmarNancy AhmedMatthias KotzschSandra DierschRudolf NapieralskiDalila DarmoulManfred SchmittWilko WeichertMarion KiechleJulia DornViktor Magdolen

Published in: Journal of cancer research and clinical oncology (2018)

These results indicate that in advanced high-grade serous ovarian cancer KLK13 may become proficient for tumor-supporting functions, whereas KLK14 may have adopted tumor-suppressing activity.

Keyphrases

high grade
low grade
ejection fraction
prognostic factors
chronic kidney disease
patient reported outcomes