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Genome-wide imputation identifies novel associations and localises signals in idiopathic inflammatory myopathies.

Simon RothwellChristopher I AmosFrederick W MillerLisa G RiderIngrid E LundbergPeter K GregersenJiri VencovskyNeil McHughVidya LimayeAlbert Selva O'CallaghanMichael G HannaPedro M MachadoLauren M PachmanAnn M ReedØyvind MolbergOlivier BenvenistePernille MathiesenTimothy RadstakeAndrea DoriaJan L De BleeckerBoel De PaepeBritta MaurerWilliam E OllierLeonid PadyukovTerrance P O'HanlonAnnette LeeLucy R WedderburnHector ChinoyJanine A Lambnull null
Published in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
We report novel and strong associations in IIM and PM, and localise signals to single genes and immune cell types. This article is protected by copyright. All rights reserved.
Keyphrases
  • genome wide
  • dna methylation
  • copy number
  • particulate matter
  • air pollution
  • heavy metals
  • polycyclic aromatic hydrocarbons
  • risk assessment
  • genome wide identification