Where is Omicron? Comparison of SARS-CoV-2 RT-PCR and Antigen Test Sensitivity at Commonly Sampled Anatomic Sites Over the Course of Disease.

Jessica LinJennifer K FredianiGregory L DamhorstJulie A SullivanAdrianna WestbrookKaleb McLendonTyler J BaughWilliam H O'SickJohn D RobackAnne L PiantadosiJesse J WaggonerLeda BassitAnuradha RaoMorgan GreenleafJared W O'NealSeegar SwansonNira R PollockGreg S MartinWilbur A LamJoshua M Levy

Published in: medRxiv : the preprint server for health sciences (2022)

Our data suggest that SARS-CoV-2 nucleocapsid and RNA exhibited similar kinetics and diagnostic yield in three upper respiratory sample types across the duration of symptomatic disease. Collection of OP or combined nasal and OP samples does not appear to increase sensitivity versus validated nasal sampling for rapid detection of viral antigen.

Keyphrases

sars cov
respiratory syndrome coronavirus
chronic rhinosinusitis
electronic health record
big data
coronavirus disease
deep learning
artificial intelligence
nucleic acid