Uniaxial strain of cultured mouse and rat cardiomyocyte strands slows conduction more when its axis is parallel to impulse propagation than when it is perpendicular.

A BuccarelloM AzzaritoF MichoudStephanie P Lacour Jan P Kucera

Published in: Acta physiologica (Oxford, England) (2018)

Changes in cardiac conduction velocity caused by acute stretch do not only depend on the magnitude of strain but also on its orientation relative to impulse propagation. This dependence is due to different effects on tissue resistance.

Keyphrases

liver failure
respiratory failure
endothelial cells
oxidative stress
left ventricular
angiotensin ii
aortic dissection
blood flow
heart failure
intensive care unit
extracorporeal membrane oxygenation