The need for hemodialysis is associated with increased mortality in mechanically ventilated children: a propensity score-matched outcome study.
Madhuradhar ChegondiSushil DevarashettyNiveditha BalakumarPrithvi SendiBalagangadhar R TotapallyPublished in: Pediatric nephrology (Berlin, Germany) (2020)
Out of 100,289 mechanically ventilated children, 1393 (1.4%) underwent HD. The mortality rate was 32.5% in the HD group, compared with 8.8% in the control group (p < 0.05). Factors that were associated with higher mortality in HD patients included severe sepsis, BMT, cardiopulmonary resuscitation (CPR), and extracorporeal membrane oxygenation therapy (ECMO). After propensity score-matched analysis, HD was still significantly associated with a higher risk of mortality (31.9% vs. 22.0%, p < 0.05) CONCLUSIONS: The requirement for HD in mechanically ventilated children is associated with higher mortality.
Keyphrases
- acute respiratory distress syndrome
- extracorporeal membrane oxygenation
- cardiopulmonary resuscitation
- cardiovascular events
- cardiac arrest
- intensive care unit
- young adults
- end stage renal disease
- risk factors
- peritoneal dialysis
- acute kidney injury
- cardiovascular disease
- type diabetes
- newly diagnosed
- ejection fraction
- stem cells
- bone marrow