HLA-DR + regulatory T cells and IL-10 are associated with success or failure of desensitization outcomes.

Xiaoying Zhou Diane Dunham Sayantani B Sindher Andrew Long Andrea Fernandes Iris Chang Amal Assa'ad Jacqueline Pongracic Jonathan M Spergel Jonathan S Tam Stephen A Tilles Julie Wang Scott D Boyd Rebecca Sharon Chinthrajah Kari Christine Nadeau

Published in: Allergy (2024)

Treg cells and IL-10 cytokine production by PBMCs are associated with desensitization outcomes of omalizumab-assisted mOIT. These findings suggest potential immunological parameters that could be targeted to enhance desensitization success rates.

Keyphrases

regulatory t cells
induced apoptosis
dendritic cells
cell cycle arrest
type diabetes
metabolic syndrome
adipose tissue
cancer therapy
risk assessment
endoplasmic reticulum stress
glycemic control
climate change
weight loss
human health
pi k akt