Deciphering the genetic and epigenetic landscape of pediatric bithalamic tumors.

Arnault Tauziède-EspariatMarie-Anne DebilyDavid CastelJacques GrillStéphanie PugetAlexandre RouxRaphaël SaffroyGuillaume GauchotteEllen WahlerLauren HastyFabrice ChrétienEmmanuèle LechaptVolodia Dangouloff-RosNathalie BoddaertPhilipp SieversPascale Varlet

Published in: Brain pathology (Zurich, Switzerland) (2021)

Pediatric bithalamic gliomas encompass several histomolecular tumoral types from benign to malignant and underlines the central role of a comprehensive neuropathological review, including immunohistochemistry, genetic, and epigenetic analyses, to achieve an accurate diagnosis.

Keyphrases

dna methylation
genome wide
gene expression
copy number
high resolution
single cell