Cognitive impairment and markers of optical neurodegeneration in early multiple sclerosis.

Renata SilvaPedro CoelhoMafalda SeabraInês LaranjinhaDaniela VieiraOctávia CostaJennifer JesusAna Cláudia FonsecaSónia CostaInês FerreiraJoão LemosCláudia SousaJosé ValeMaria José SáLuis Ruano

Published in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology (2022)

Cognitive impairment was frequent in our sample of early MS. However, no association with reduced pRNFL or mGCL thickness was found. When compared to OCT, cognitive assessment could provide an earlier marker of neurodegeneration in MS.

Keyphrases

cognitive impairment
multiple sclerosis
mass spectrometry
optical coherence tomography
ms ms
white matter
high resolution
high speed