Radioembolization of hepatocarcinoma with 90Y glass microspheres: treatment optimization using the dose-toxicity relationship.

Carlo ChiesaM MiraS BhooriG BormoliniM MaccauroC SpreaficoT CascellaA CavalloM C De NileS MazzagliaA CapozzaG TagliabueA BrusaA MarchianòE SeregniV Mazzaferro

Published in: European journal of nuclear medicine and molecular imaging (2020)

Given the low predictive accuracy of 99mTc-MAA on lesion absorbed dose reported by several authors, an optimized TARE with 90Y glass microspheres with lobar injection 4 days after reference time should aim at an absorbed dose averaged over the whole non-tumoural liver of 50 Gy/90 Gy for basal bilirubin higher/lower than 1.1 mg/dL, respectively.

Keyphrases

molecularly imprinted
ultrasound guided
high resolution
combination therapy
simultaneous determination
solid phase extraction