Spontaneously hypertensive rats can become hydrocephalic despite undisturbed secretion and drainage of cerebrospinal fluid.
Sara Diana LolansenDagne BarbuskaiteFenghui YeJianming XiangRichard F KeepNanna MacAulayPublished in: Fluids and barriers of the CNS (2023)
Hydrocephalus development in SHRs does not associate with elevated ICP and does not require increased CSF secretion or inefficient CSF drainage. SHR hydrocephalus thus represents a type of hydrocephalus that is not life threatening and that occurs by unknown disturbances to the CSF dynamics.