Allergen immunotherapy for IgE-mediated food allergy: a systematic review and meta-analysis.

U NurmatovSangeeta DhamiS ArasiG B PajnoM Fernandez-RivasA MuraroG RobertsC AkdisM Alvaro-LozanoK BeyerC Bindslev-JensenW BurksG du ToitM EbisawaP EigenmannE KnolM MakelaKari Christine Nadeau Corina M BersetN PapadopoulosL K PoulsenC SackesenH SampsonA F SantosR van ReeF TimmermansA Sheikh

Published in: Allergy (2017)

AIT may be effective in raising the threshold of reactivity to a range of foods in children with IgE-mediated food allergy whilst receiving (i.e. desensitization) and post-discontinuation of AIT. It is, however, associated with a modest increased risk in serious systemic adverse reactions and a substantial increase in minor local adverse reactions. More data are needed in relation to adults, long term effects, the impact on QoL and the cost-effectiveness of AIT.

Keyphrases

electronic health record
big data
emergency department
deep learning
allergic rhinitis