Vascular endothelial growth factor antagonist peptides inhibit tumor growth and metastasis in breast cancer through repression of c-src and STAT3 genes.

Maedeh Bejari Soheila Talesh Sasani S Mohsen Asghari Mozhgan Nabatzade Kolshan

Published in: Molecular biology reports (2023)

In conclusion, peptides VGB1, 3, and 4, could be effective therapeutic molecules in breast cancer by inhibiting angiogenesis and progression of the disease.

Keyphrases

vascular endothelial growth factor
endothelial cells
cell proliferation
tyrosine kinase
genome wide
gene expression
transcription factor
young adults
dna methylation