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Disentangling the relationship between social cognition, executive functions and behaviour changes in amyotrophic lateral sclerosis.

Francesca PalumboBarbara IazzolinoStefano CallegaroAntonio CanosaUmberto ManeraRosario VastaMaurizio GrassanoEnrico MatteoniGiorgio PellegrinoPaolina SalamoneLaura PeottaFederico CasaleGiuseppe FudaCristina MogliaAdriano ChioAndrea Calvo
Published in: Journal of neurology, neurosurgery, and psychiatry (2024)
SC is overall independent of EF in ALS, with ToM only partially associated with specific EF measures, and behaviour changes associated with emotional disorders. The influence of SC on cognitive categorisation and the frequent identification of a subclinical SC impairment have implications in a clinical setting, considering the substantial impact of cognitive impairment on disease burden and therapeutic choices.
Keyphrases
  • cognitive impairment
  • healthcare
  • mental health
  • white matter
  • risk factors
  • multiple sclerosis
  • bioinformatics analysis