Epidemiological and clinical characteristics of pregnant women and neonates with COVID-19 in Northwest Mexico.
Nidia León-SicairosUriel A Angulo-ZamudioMireya Pacheco-AvilaIvan Medina-RamirezJorge Velazquez-RomanJorge Angulo-RochaFrancisco Antonio Martinez-VillaHector Flores-VillaseñorJesus J Martinez-GarciaJaime Sanchez-CuenOscar Garzon-LopezMartha Guel-GomezHector Melesio Cuen-DiazMario Francisco Barajas-OlivasAbraham Campos-RomeroJonathan Alcántar-FernándezMarco A Luna-Ruiz EsparzaCanizalez-Román AdrianPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)
A total of 11.2% (13/116) of the pregnant women were RT-PCR+, 25% (29/116) were IgG+ and 4.3% (5/116) were positive for both tests. Symptoms such as rhinorrhea (P = .04), cough (P = .02) and polypnea (P = .04) in pregnant women were related to COVID-19, also leukocyte index was higher in pregnant women with COVID-19 (P = .03), but the associations were lost after the Bonferroni correction. No laboratory parameters or underlying diseases were associated with COVID-19, and most infected pregnant women had mild cases. We found an association between the influenza vaccine and less common COVID-19 symptoms in pregnant women who were infected (P = .01). A total of 7.2% (6/84) of neonates were RT-PCR+, 35.7% (30/84) were IgG+, and there were no symptoms or underlying diseases associated with neonates who were infected. In conclusion, this work demonstrated that some symptoms were related to COVID-19, most pregnant women and neonates had mild cases, and the influenza vaccine could decrease the severity of COVID-19 cases in pregnant women.