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STRIP2 is regulated by the transcription factor Sp1 and promotes lung adenocarcinoma progression via activating the PI3K/AKT/mTOR/MYC signaling pathway.

Junfan PanYuan ZhangLiu HeYue WuWeijin XiaoJing ZhangYiquan Xu
Published in: Genomics (2024)
Our study identifies STRIP2 is a key driver of LUAD progression and a potential therapeutic target.
Keyphrases
  • signaling pathway
  • transcription factor
  • pi k akt
  • epithelial mesenchymal transition
  • induced apoptosis
  • oxidative stress
  • cell proliferation