Diffuse alveolar haemorrhage as a rare complication of antiphospholipid syndrome.
Ishith SethShyam Prakaash Bhagavata SrinivasanGabriella BullochDong Seok YiAnthony FrankelKelvin HsuFreda PassamRoger GarsiaTamera J CortePublished in: Respirology case reports (2022)
Diffuse alveolar haemorrhage (DAH) is a rare complication of antiphospholipid syndrome. With a mortality rate of 46%, early diagnosis and management remain an ongoing challenge. Case reports are limited, and management guidelines are not yet definitive. In this case report, we present a 43-year-old male with DAH who required high-dose oral steroids, intravenous methylprednisolone cyclophosphamide and rituximab over 18 months to control life-threatening episodes of pulmonary bleeding.
Keyphrases
- high dose
- case report
- low dose
- stem cell transplantation
- low grade
- pulmonary hypertension
- diffuse large b cell lymphoma
- cardiovascular events
- atrial fibrillation
- clinical practice
- risk factors
- locally advanced
- hodgkin lymphoma
- type diabetes
- squamous cell carcinoma
- cardiovascular disease
- coronary artery disease
- rectal cancer