Rs4612666 Polymorphism of the NLRP3 Gene Is Associated with the Occurrence of Large Artery Atherosclerotic Ischemic Strokes and Microembolic Signals.

Lufeng ChengRuihua YinShaonan YangXudong Pan Aijun Ma

Published in: BioMed research international (2018)

The NLRP3 rs4612666 gene polymorphism may be related to the occurrence of LAA IS and MES, suggesting that the NLRP3 gene polymorphism increases the susceptibility of LAA IS by changing the plaque vulnerability.

Keyphrases

risk assessment
nlrp inflammasome
climate change
genome wide
copy number
ischemia reperfusion injury
dna methylation
gene expression
brain injury
cerebral ischemia
transcription factor