Skin microbiome and its association with host cofactors in determining atopic dermatitis severity.
Luise RauerM ReigerM BhattacharyyaP M BrunnerJ G KruegerE Guttman-YasskyC Traidl-HoffmannA U NeumannPublished in: Journal of the European Academy of Dermatology and Venereology : JEADV (2022)
Our results specify the frequently reported "reduced diversity" of the AD-related skin microbiome to reduced Evenness, which was in turn mainly driven by S. aureus relative abundance, rather than to a reduced microbiome Richness. Finding associations between AD severity, the skin microbiome and patient's cofactors is a key aspect in developing new personalized AD treatments, particularly those targeting the AD microbiome.