Age-related white matter changes revealed by a whole-brain fiber-tracking method in bipolar disorder compared to major depressive disorder and healthy controls.

Yoshikazu MasudaGo OkadaMasahiro TakamuraChiyo ShibasakiAtsuo Yoshino Satoshi YokoyamaNaho IchikawaShiho OkuhataTetsuo KobayashiShigeto YamawakiYasumasa Okamoto

Published in: Psychiatry and clinical neurosciences (2020)

Significant FA reductions were found in BD patients after controlling for age, indicating that abnormal white matter integrity in BD may occur at a younger age rather than developing progressively with age.

Keyphrases

white matter
major depressive disorder
bipolar disorder
multiple sclerosis
end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
patient reported outcomes
cerebral ischemia
blood brain barrier