A pilot study on the effects of probiotic supplementation on neuropsychological performance and microRNA-29a-c levels in antiretroviral-treated HIV-1-infected patients.
Giancarlo CeccarelliMariangela FratinoCarla SelvaggiNoemi GiustiniSara SerafinoIvan SchietromaGiuseppe Corano ScheriPaolo PavoneGiulia PassavantiDanilo Alunni FegatelliIvano MezzaromaGuido AntonelliVincenzo VulloCarolina ScagnolariGabriella d'EttorrePublished in: Brain and behavior (2017)
In conclusion, we observed that HIV patients treated with 6 months of this probiotic supplementation appear to have an improvement in some neurocognitive functions; moreover, this approach is safe and did not modify significantly the levels of miRNA in CSF. Further studies are needed to better understand the contribution of the probiotics in modulating gut-brain-axis in HIV patients.
Keyphrases
- antiretroviral therapy
- hiv infected patients
- hiv infected
- hiv positive
- human immunodeficiency virus
- hiv aids
- newly diagnosed
- hiv testing
- hepatitis c virus
- men who have sex with men
- ejection fraction
- end stage renal disease
- prognostic factors
- south africa
- white matter
- resting state
- patient reported
- subarachnoid hemorrhage