Pharmacokinetic Study of 14 C-Radiolabeled p-Boronophenylalanine (BPA) in Sorbitol Solution and the Treatment Outcome of BPA-Based Boron Neutron Capture Therapy on a Tumor-Bearing Mouse Model.
Tsubasa WatanabeTomohiro YoshikawaHiroki TanakaYuko KinashiGenro KashinoShin-Ichiro MasunagaToshimitsu HayashiKoki UeharaKoji OnoMinoru SuzukiPublished in: European journal of drug metabolism and pharmacokinetics (2023)
In this report, we demonstrate the efficacy of BPA in sorbitol solution as the boron source in BNCT.