Validation of the PRUCISION Instruments in Pediatric Patients with Progressive Familial Intrahepatic Cholestasis.

Chad GwaltneyCristina IvanescuLisa KarlssonNatalie WarholicLise KjemsPatrick Horn

Published in: Advances in therapy (2022)

The PRUCISION ObsRO instrument is reliable, valid, and sensitive to change, supporting its use as a tool to measure pruritus and sleep disturbance in patients with PFIC and other pediatric cholestatic liver diseases.

Keyphrases

liver injury
multiple sclerosis
drug induced
patient reported outcomes
early onset
sleep quality
liver fibrosis
depressive symptoms
atopic dermatitis