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Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study.

Joo-Yeon Engelen-LeeMatthijs C BrouwerEleonora AronicaDiederik van de Beek
Published in: Annals of intensive care (2018)
The aetiology of DCT complicating pneumococcal meningitis seems to be of multifactorial aetiology and includes vascular inflammation, thromboembolism of large arteries and infectious intracranial aneurysms. Pneumococcal cell wall components can be observed for weeks after pneumococcal meningitis and may be a source of resurging inflammation after the initial immunosuppression by dexamethasone.
Keyphrases
  • cell wall
  • oxidative stress
  • cerebrospinal fluid
  • pulmonary embolism
  • low dose
  • high dose
  • blood brain barrier
  • cerebral ischemia
  • cerebral blood flow