Janus kinase inhibitors differentially inhibit specific cytokine signals in the mesenteric lymph node cells of IBD patients.

Duncan C HindmarchSofya MalashankaDonna M ShowsAstrid S ClarkeJames D Lord

Published in: Journal of Crohn's & colitis (2023)

Despite their similarities, differences exist in the relative potencies of different JAKinibs against distinct cytokine families to explain their clinical efficacy.

Keyphrases

lymph node
end stage renal disease
induced apoptosis
ejection fraction
newly diagnosed
chronic kidney disease
prognostic factors
neoadjuvant chemotherapy
early stage
signaling pathway
cell proliferation
patient reported