Immunomodulatory tetracyclines shape the intestinal inflammatory response inducing mucosal healing and resolution.

Jose Garrido MesaA Rodríguez-NogalesF AlgieriT VezzaL Hidalgo-GarciaM Garrido-BarrosM P UtrillaF GarciaN ChuecaM E Rodriguez-CabezasN Garrido-MesaJ Gálvez

Published in: British journal of pharmacology (2018)

Immunomodulatory tetracyclines potentiate protective immune pathways leading to mucosal healing and resolution, representing a promising drug reposition strategy for the treatment of intestinal inflammation.

Keyphrases

inflammatory response
single molecule
ulcerative colitis
oxidative stress
lipopolysaccharide induced
adverse drug
electronic health record