Risk of intracranial haemorrhage and ischaemic stroke after convexity subarachnoid haemorrhage in cerebral amyloid angiopathy: international individual patient data pooled analysis.
Isabel Charlotte HostettlerDuncan WilsonCatherine Arnold FiebelkornDiane AumSebastián Francisco AmerisoFederico EberbachMarkus BeitzkeTimothy John KleinigThanh G PhanSarah MarchinaRomain SchneckenburgerMaría Carmona-IraguiAndreas CharidimouIsabelle MourandSara ParreiraGareth AmblerHans Rolf JägerShaloo SinghalJohn LyHenry MaEmmanuel TouzéRuth GeraldesAna Catarina FonsecaTeresa MeloPierre LabaugePierre-Henry LefèvreAnand ViswanathanSteven Mark GreenbergJuan ForteaMarion ApoilMarion BoulangerFausto ViaderSandeep KumarVelandai SrikanthAshan KhurramFranz FazekasVeronica BrunoGregory Joseph ZipfelDaniel RefaiAlejandro RabinsteinJonathan Graff-RadfordDavid John WerringPublished in: Journal of neurology (2021)
Patients with cSAH associated with probable or possible CAA have high risk of future ICH and recurrent cSAH. Convexity SAH associated with probable (vs possible) CAA is associated with increased risk of ICH, and cSAH but not ischemic stroke. Our data provide precise risk estimates for key vascular events after cSAH associated with CAA which can inform management decisions.