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Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection.

Elena DenisenkoReto GulerMusa MhlangaHarukazu SuzukiFrank BrombacherSebastian Schmeier
Published in: BMC genomics (2019)
Our findings suggest the importance of macrophage host transcriptional enhancers during M.tb infection. Our study extends current knowledge of the regulation of macrophage responses to M.tb infection and provides a basis for future functional studies on enhancer-gene interactions in this process.
Keyphrases
  • mycobacterium tuberculosis
  • adipose tissue
  • healthcare
  • transcription factor
  • gene expression
  • pulmonary tuberculosis
  • genome wide
  • copy number
  • binding protein
  • dna methylation
  • drug induced
  • heat shock protein