Novel insights into the substrate involved in maintenance of ventricular fibrillation: results from continuous multipolar mapping in a canine model.
Fatima M EzzeddineRobert C WardZhi JiangJason A TriKolade AgboolaTiffany HuFahad LodhiNicholas Y TanThomas P LadasGeorgios ChristopoulosAlan M SugrueElena G TolkachevaFreddy Del-Carpio MunozChristopher J McLeodSamuel J AsirvathamChristopher V DeSimonePublished in: Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing (2022)
This study describes the evolution of VF from electrical initiation to spontaneous VF termination without hemodynamic support in healthy canines. These data are hypothesis-generating and suggest that critical substrate for VF maintenance may reside in both the distal RV and LV depending on stage of VF. Further studies are needed to replicate these findings with hemodynamic support and to translate such findings into clinical practice. Ventricular fibrillation maintenance may be dependent on critical structures in the distal RV. ECG: electrocardiogram; LV: left ventricle; RV: right ventricle; RVOT: right ventricular outflow tract; VF: ventricular fibrillation.
Keyphrases
- mycobacterium tuberculosis
- left ventricular
- heart failure
- clinical practice
- catheter ablation
- high resolution
- pulmonary hypertension
- mitral valve
- pulmonary artery
- minimally invasive
- heart rate variability
- electronic health record
- heart rate
- amino acid
- atrial fibrillation
- coronary artery
- blood pressure
- machine learning
- big data
- congenital heart disease
- pulmonary arterial hypertension
- data analysis