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Effect of IRT5 probiotics on dry eye in the experimental dry eye mouse model.

Jayoon MoonJin Suk RyuJun Yeop KimSin-Hyeog ImMee-Kum Kim
Published in: PloS one (2020)
In experimental dry eye model, IRT5 probiotics treatment partially improves experimental dry eye by increasing tear secretion which was associated with and influenced by the change in intestinal microbiome. Also, intestinal microbiome may affect the lacrimal gland through a different mechanism other than regulating inflammation.
Keyphrases
  • mouse model
  • combination therapy
  • replacement therapy