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Describing the status of reproductive ageing simply and precisely: A reproductive ageing score based on three questions and validated with hormone levels.

Kai TriebnerAne JohannessenCecilie SvanesBénédicte LeynaertBryndís BenediktsdóttirPascal DemolyShyamali C DharmageKarl A FranklinJoachim HeinrichMathias HolmDeborah JarvisEva LindbergJesús Martínez Moratalla RoviraNerea Muniozguren AgirreJosé Luis Sánchez RamosVivi SchlünssenSvein Magne SkulstadSteinar HustadFrancisco J RodriguezFrancisco Gómez Real
Published in: PloS one (2020)
The RAS provides a useful and valid tool for describing the status of reproductive ageing accurately, on a continuous scale from 0.00 to 1.00, based on simple questions and without requiring blood sampling. The score allows for a more precise differentiation than the conventional categorisation in pre-, peri- and postmenopause. This is useful for epidemiological research and clinical trials.
Keyphrases
  • clinical trial
  • phase ii
  • study protocol
  • wild type