Molecular imaging of arterial fibroblast activation protein: association with calcified plaque burden and cardiovascular risk factors.
Aleksander KosmalaSebastian E SerflingKerstin MichalskiThomas LindnerAndreas SchirbelTakahiro HiguchiPhilipp E HartrampfThorsten DerlinAndreas K BuckAlexander WeichRudolf A WernerPublished in: European journal of nuclear medicine and molecular imaging (2023)
Ga]Ga-FAPI-04 PET identifies arterial wall lesions and is linked to marked calcification and overall calcified plaque burden, but is not consistently associated with cardiovascular risk. Apparent wall uptake may be partially explained by image noise.
Keyphrases
- pet ct
- cardiovascular risk factors
- cardiovascular disease
- coronary artery disease
- metabolic syndrome
- positron emission tomography
- chronic kidney disease
- deep learning
- genome wide
- risk factors
- computed tomography
- air pollution
- magnetic resonance imaging
- amino acid
- diffusion weighted imaging
- protein protein
- type diabetes
- machine learning
- dna methylation
- contrast enhanced