The Prognostic and Therapeutic Role of Genomic Subtyping by Sequencing Tumor or Cell-Free DNA in Pulmonary Large-Cell Neuroendocrine Carcinoma.

Minglei ZhuoYanfang GuanXue YangLingzhi HongYuqi WangZhongwu LiRunzhe ChenHussein A AbbasLianpeng ChangYuhua GongNan WuJia ZhongZhi DongXiang ZhuJianjie LiYuyan WangTongtong AnMeina WuZiping WangJiayin WangEmily B RoartyWaree RinsurongkawongJeff LewisJack A RothStephen G SwisherJ Jack LeeJohn Victor HeymachIgnacio I WistubaNeda KalhorLing YangXin YiP Andrew FutrealBonnie S GlissonXuefeng XiaJianjun ZhangJun Zhao

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2019)

Genomic subtyping has potential in prognostication and therapeutic decision-making for patients with LCNEC and cfDNA analysis may be a reliable alternative for genomic profiling of LCNEC.

Keyphrases

single cell
copy number
decision making
pulmonary hypertension
stem cells
human health