Cellular and Clinical Analyses of Autologous Bone Marrow Aspirate Injectate for Knee Osteoarthritis: A Pilot Study.

Kristina WellsMichael KleinNicole HurwitzKristen SantiagoJennifer ChengZafir AbutalibNicholas BeattyGregory E Lutz

Published in: PM & R : the journal of injury, function, and rehabilitation (2020)

The cellular content of BMA samples varied widely between patients and was lower than the anticipated yield reported by the device's manufacturer. However, intra-articular BMA injections for knee OA in a small pilot cohort appeared to be safe with potential therapeutic value. Larger, prospective, double-blinded studies are warranted.

Keyphrases

knee osteoarthritis
bone marrow
end stage renal disease
chronic kidney disease
ejection fraction
newly diagnosed
prognostic factors
platelet rich plasma
clinical trial
total knee arthroplasty
cell therapy
patient reported outcomes
case control