Unresectable infantile myofibroma discovered in utero.
Shannon WesselBen J FriedmanTor A ShwayderPublished in: Pediatric dermatology (2024)
The authors present a case of a proliferative nodule located beneath an infant's lower lip that was initially discovered on prenatal ultrasound and fetal magnetic resonance imaging (MRI). Biopsy revealed a smooth muscle actin-positive spindled cell proliferation with hemangiopericytoma-like vessels consistent with infantile myofibromatosis (IM). Since the location prevented surgical management, the clinicians opted to observe the lesion. Ultimately, the lesion fully regressed on its own confirming conservative management is an option for isolated IM.
Keyphrases
- magnetic resonance imaging
- smooth muscle
- cell proliferation
- contrast enhanced
- computed tomography
- ultrasound guided
- pregnant women
- diffusion weighted imaging
- palliative care
- cell cycle
- single cell
- locally advanced
- squamous cell carcinoma
- fine needle aspiration
- liver metastases
- pi k akt
- magnetic resonance
- radiation therapy
- cell migration