The Role of Immunotherapy in the Management of Esophageal Cancer in Patients Treated with Neoadjuvant Chemoradiation: An Analysis of the National Cancer Database.

Panagiotis TasoudisVasiliki ManakiYoshiko IwaiSteven A Buckeridge Audrey L Khoury Chris B AgalaBenjamin E HaithcockGita N ModyJason M Long

Published in: Cancers (2024)

In this retrospective analysis of the NCDB, receiving adjuvant immunotherapy offered a significant survival advantage compared to no immunotherapy and neoadjuvant immunotherapy in the treatment of esophageal adenocarcinoma. The addition of neoadjuvant immunotherapy to patients treated with neoadjuvant chemoradiation did not improve survival in this cohort. Further studies are warranted to investigate the long-term outcomes of immunotherapy in esophageal cancer.

Keyphrases

rectal cancer
locally advanced
lymph node
squamous cell carcinoma
radiation therapy
early stage
combination therapy
replacement therapy
case control
smoking cessation