Risk factors for knee osteoarthritis after traumatic knee injury: a systematic review and meta-analysis of randomised controlled trials and cohort studies for the OPTIKNEE Consensus.
Jackie L WhittakerJustin M LoscialeCarsten Bogh JuhlJonas Bloch ThorlundMatilde LundbergLinda K TruongMaxi MiciakBelle Lore van MeerAdam Geoffrey CulvenorKay M CrossleyEwa M RoosL Stefan LohmanderMarienke van MiddelkoopPublished in: British journal of sports medicine (2022)
Moderate-certainty evidence suggests that various single and multistructure knee injuries (beyond ACL tears) increase the odds of symptomatic OA. Risk factor heterogeneity, high risk of bias, and inconsistency in risk factors and OA definition make identifying treatment targets for preventing post-traumatic knee OA challenging.