Myelin water imaging depends on white matter fiber orientation in the human brain.
Christoph BirklJonathan DoucetteMichael FanEnedino Hernández-TorresAlexander RauscherPublished in: Magnetic resonance in medicine (2020)
White matter fiber orientation induces a strong systematic bias on the estimation of the apparent MWF. This finding has implications for future research and the interpretation of MWI results in previously published studies.