Eosinophilic features in clear cell renal cell carcinoma correlate with outcomes of immune checkpoint and angiogenesis blockade.
Takashi YoshidaChisato OheJunichi IkedaNaho AtsumiHaruyuki OhsugiMotohiko SugiKoichiro HigasaRyoichi SaitoKoji TsutaTadashi MatsudaHidefumi KinoshitaPublished in: Journal for immunotherapy of cancer (2022)
The histological phenotype based on the eosinophilic features, which are linked to major immunological mechanisms of ccRCC, was significantly correlated with therapeutic efficacy.