Olanzapine for the prophylaxis and rescue of chemotherapy-induced nausea and vomiting: a systematic review, meta-analysis, cumulative meta-analysis and fragility assessment of the literature.

Ronald ChowJørn HerrstedtMatti AaproLeonard ChiuHenry LamElizabeth PrsicMichael LockCarlo DeAngelisRudolph M Navari

Published in: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer (2021)

Further RCTs are needed in the setting of MEC patients and administration of olanzapine at a lower 5-mg dose, which may be given to reduce the sedative effect of olanzapine at 10 mg.

Keyphrases

chemotherapy induced
systematic review
end stage renal disease
meta analyses
ejection fraction
chronic kidney disease
newly diagnosed
peritoneal dialysis
prognostic factors
case control
patient reported outcomes