Levels of Neurofilament Light at the Preataxic and Ataxic Stages of Spinocerebellar Ataxia Type 1.

Carlo WilkeDavid MengelLudger SchölsHolger HengelMaria RakowiczThomas KlockgetherAlexandra DürrAlessandro FillaBela MeleghRebecca SchüleKathrin ReetzHeike JacobiMatthis Synofzik

Published in: Neurology (2022)

This study provides Class III evidence that NfL levels are increased in both ataxic and preataxic SCA1 and are associated with ataxia onset.

Keyphrases

early onset
cerebrospinal fluid