Potentially functional variants of CHMP4A and PANX1 in the pyroptosis-related pathway predict survival of patients with non-oropharyngeal head and neck squamous cell carcinoma.

Xiaozhun TangHuiling WangHongliang LiuGuojun LiErich M SturgisSanjay SheteWenjie Jiao

Published in: Molecular carcinogenesis (2024)

Genetic variants in the pyroptosis pathway genes may predict the survival of NON-ORO HNSCC patients, likely by reducing the gene expression, but our findings need to be replicated by larger studies.

Keyphrases

gene expression
end stage renal disease
newly diagnosed
chronic kidney disease
nlrp inflammasome
dna methylation
genome wide
copy number
transcription factor