The association between antigenemia, histology with immunohistochemistry, and mucosal PCR in the diagnosis of ulcerative colitis with concomitant human cytomegalovirus infection.

Tsukasa YamawakaHiroki KitamotoMasanori NojimaTomoe KazamaKohei WagatsumaKeisuke IshigamiShuji YamamotoYusuke HonzawaMinoru MatsuuraHiroshi SenoHiroshi Nakase

Published in: Journal of gastroenterology (2022)

The antigenemia assay and histopathological test with IHC were significantly associated with the HCMV-DNA copy number in colonic tissues. Moreover, endoscopic examination with the UCEIS can help diagnose the HCMV colitis in UC patients.

Keyphrases

ulcerative colitis
copy number
mitochondrial dna
end stage renal disease
endothelial cells
ejection fraction
newly diagnosed
genome wide
gene expression
prognostic factors
dna methylation
single molecule
single cell
real time pcr