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Association between CD8+ tumor-infiltrating lymphocytes and prognosis of non-small cell lung cancer patients treated with PD-1/PD-L1 inhibitors: a systematic review and meta-analysis.

Qi-Ming ZhengYuan-Yuan LiYe-Peng WangGuo-Xiang LiMeng-Meng ZhaoZhi-Gang Sun
Published in: Expert review of anticancer therapy (2023)
In spite of the location of CD8+ TILs, high densities of CD8+ TILs were predictive of treatment outcomes in NSCLC patients treated with PD-1/PD-L1 inhibitors. However, high CD8+ TILs in peripheral blood had no predictive effect.
Keyphrases
  • peripheral blood
  • small cell lung cancer
  • nk cells
  • epidermal growth factor receptor
  • brain metastases