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In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion.

Stella F S XuDaniel B AndersenJose M G IzarzugazaRune Ehrenreich KuhreJens Juul Holst
Published in: Acta physiologica (Oxford, England) (2020)
Somatostatin is a powerful and tonic inhibitor of glucagon secretion from the rat pancreas and is required for glucose to inhibit glucagon secretion.
Keyphrases
  • oxidative stress
  • blood glucose
  • diabetic rats
  • type diabetes
  • metabolic syndrome
  • blood pressure
  • weight loss