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Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides.

Kyle BooneCate WisdomKyle CamardaPaulette SpencerCandan Tamerler
Published in: BMC bioinformatics (2021)
Our results demonstrate that AMP design can be customized to maintain activity and simplify production. To our knowledge, this is the first time when codon-based genetic algorithms combined with rough set theory methods is used for computational search on peptide sequences.
Keyphrases
  • machine learning
  • deep learning
  • artificial intelligence
  • genome wide
  • big data
  • copy number
  • healthcare
  • protein kinase
  • anti inflammatory
  • gene expression