Combining genetic algorithm with machine learning strategies for designing potent antimicrobial peptides.
Kyle BooneCate WisdomKyle CamardaPaulette SpencerCandan TamerlerPublished in: BMC bioinformatics (2021)
Our results demonstrate that AMP design can be customized to maintain activity and simplify production. To our knowledge, this is the first time when codon-based genetic algorithms combined with rough set theory methods is used for computational search on peptide sequences.