Gut microbiota from green tea polyphenol-dosed mice improves intestinal epithelial homeostasis and ameliorates experimental colitis.

Zhenhua WuShimeng HuangTiantian LiNa LiDandan HanBing ZhangZhenjiang Zech XuShiyi ZhangJiaman PangShilan WangGuolong ZhangJiangchao ZhaoJun-Jun Wang

Published in: Microbiome (2021)

This study provides the first data indicating that oral EGCG ameliorated the colonic inflammation in a gut microbiota-dependent manner. Our findings provide novel insights into EGCG-mediated remission of IBD and EGCG as a potential modulator for gut microbiota to prevent and treat IBD. Video Abstract.

Keyphrases

ulcerative colitis
electronic health record
type diabetes
big data
mouse model
machine learning
disease activity
human health
skeletal muscle
climate change
artificial intelligence