Influence of Protein Carbonylation on Human Adipose Tissue Dysfunction in Obesity and Insulin Resistance.

M Carmen Navarro-RuizM Carmen Soler-VázquezAlberto Díaz-Ruiz Juan Ramón PeinadoAndrea Nieto CalongeJulia Sánchez-CeinosCarmen Tercero-AlcázarJaime López-AlcaláOriol Alberto Rangel-ZuñigaAntonio MembrivesJose Lopez-MirandaMaría M MalagónRocío Guzmán-Ruiz

Published in: Biomedicines (2022)

The adipose tissue carbonylome contributes to understanding the molecular mechanism driving adipocyte dysfunction and identifies possible adipose tissue carbonylated targets in obesity-associated insulin resistance.

Keyphrases

insulin resistance
adipose tissue
high fat diet
high fat diet induced
polycystic ovary syndrome
metabolic syndrome
skeletal muscle
endothelial cells
oxidative stress
type diabetes
genome wide
gene expression
induced pluripotent stem cells
protein protein
body mass index
weight loss
binding protein
small molecule